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Anti-oxidants
Antioxidants
are free radical scavengers. Free radicals are by-products
of various metabolic functions and may also be formed by exposure
to radiation, toxic chemicals, overexertion and by overexposure to the
sun. Free radicals (molecules with unpaired electrons) are
used by the immune system to destroy bacteria and virus-infected
cells. The liver also uses these molecules to detoxify harmful
chemicals. However, free radicals can also cause molecular damage to
cells, impair the immune system, and ultimately lead to diseases.
Naturally occurring enzymes (superoxide dismutase(SOD), methione reductase,
catalase and glutathione peridoxidase) protect the body from free radicals
by neutralizing them. The work of these enzymes can be supplemented
by a diet rich in antioxidants. Taking too many antioxidants can
result in feeling fatigued.
There have been some concern in the past that taking antioxidants concurrently
while undergoing some types of chemotherapy might interfere with the
potency of the chemothreapy treatment. Cisplatin is a chemotherapy treatment
that generates free radicals in cancerous cells. While it would be logical
to assume that taking antioxidants might interfere with this type of
treatment, there have been two studies that have indicated otherwise.
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"Two
major scientific papers recently appeared strongly supporting
the concurrent use of antioxidants and chemotherapy. One of these
is a randomized controlled trial, the other a laboratory experiment.
Both conclude that the antioxidant vitamin E (alpha-tocopherol)
protects against nerve damage from the common chemotherapy drug
cisplatin, without interfering with its effectiveness.."
"The Moss Reports Newsletter" April 18, 2003
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Ralph W. Moss,
Ph.D., author of numerous books on alternative cancer treatment
issue, is referring to the following studies:
Pace A, et al. Neuroprotective effect of vitamin E supplementation
in patients treated with cisplatin chemotherapy. J Clin Oncol. 2003
Mar 1;21(5):927-31.
Leonetti C, et al. Alpha-tocopherol protects against cisplatin-induced
toxicity without interfering with antitumor efficacy. Int J Cancer.
2003 Mar 20;104(2):243-50
Both of these studies focused on the effects of vitamin E supplementation
while undergoing treatments with Cisplatin, To read more about these
two studies, visit the archives of the Moss
Reports newsletter and view the article "A Boost for Antioxidants"
in the April 18, 2003 newsletterat his website www.CancerDecisions.com.
Folowing are nutrients that have antioxidative properties.
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Coenzyme Q10 (ubiquinone) is
a vitamin-like substance that resembles vitamin E, but which may
be an even more powerful antioxidant. There are ten common coenzyme
Qs, but coenzyme Q10 is the only one found
in human tissue. It plays a crucial role in the effectiveness of
the immune system and in the aging process.
Coenzyme Q10 has been shown to prevent cancer
and reduce the size and metastasis of induced cancers.
(Larsson)
Clinical tests are being used along with chemotherapy to reduce
the side effects of the drugs.
Mackeral, salmon and sardines contain the largest amounts of coenzyme
Q10.
WARNING: Not all products offer COQ10 in it's
purest form. Its natural color is bright yellow and has very little
taste in the powdered form. It should be kept away from heat and
light. Pure COQ10 will deteriorate in temperatures
above 115°F.
For more information, read Jack Challem's article Coenzyme
Q10: it May Just Be the Miracle Vitamin of the 1990's
Vitamin E protects the essential fatty acids from oxidation
and free radicals. It has been found to prevent tumors produced by
carcinogenic substances and helps to form red blood cells. Vitamin
E rich foods include olive and flaxseed oil, dark green vegetables,
tomatoes, fresh vegetable oils, whole grains, oatmeal, peanuts, sunflower
seeds, almonds, peaches, and prunes.
When Vitamin E binds with a free radical, it creates a harmless radical
along with a potentially harmful "E-radical". E-radicals
can combine with a carotenoid (Vitimin A) and create a harmless radical
along with a potentially harmful carotenoid radical. The carotenoid
radical, when it meets Vitamin C becomes a C radical (water soluable)
and is then flushed out of the system. For this reason, it is important
to combine your intake of Vitamins A and E with Vitamin C.
- Selenium Selenium works in conjunction with Vitamin E. See
section above.
- Vitamin A
- Vitamin C encourages the production of interferon, a protein
in cells that helps keep viruses from spreading. Vitamin C rich fruits
include kiwi fruit, strawberries, cantaloupe, grapefruit, and lemon
juice in hot water. Vitamin C rich vegetables include sweet red pepper,
broccoli, kale, alfalfa sprouts, and cabbage.
Avoid taking mega-doses of vitamin C which can cause excess levels
of iron to build up. Mega-doses of vitamin C can also interfere
with some cancer treatments. Consuming vitamin-C rich food, however
provides us with a safe level of vitamin C that is easily absorbed
and packaged with other vitamins, phytochemicals, and nutrients that
give us added protection.
"Esterfied" Vitamin C is pH nuetral and is not acidic to
the stomach like absorbic acid. Non-esterfied Vitamin C is more quickly
eliminated by the body. Vitamins C and D increase the absorbtion of
calcium
- Grape Seed Extract (Pycnogenol) is high in various phytochemicals,
including a variety of bioflavonoids such as proanthrocyanins and
anthrocyanins. Anthrocyanins and other flavonoids extracted from grape
seeds are highly effective "scavengers" of harmful free
radicals. Pycnogenols have been shown to be up to 50 times more effective
than vitamin E and 20 times stronger thatn vitamin C in free-radical
nuetralizing power.
Grape seed extract is now widely prescribed in France and Italy, where
grapes are abundant, for a variety of maladies.
Pine bark extract
L-glutathione
superoxide dismutase
bioflavonoids
- BHT (Butylated Hydroxytoluene)
Alpha-lipoic acid
Plant antioxidants include garlic and ginko biloba. Seaweed is rich
in antioxidants and selenium. Wakame, kombu, nori, hijiki, arame.
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